Experimental models for posterior capsule opacification research

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Posterior Capsule Opacification: An Overview

DOS Times Vol. 12, No. 4 October, 2006 Posterior capsule opacification (PCO) and posterior chamber intraocular lens (PC IOL) decentration still remain two major complications of successful extracapsular cataract surgery (ECCE) or phacoemulsification. Ridley, who performed the first intraocular lens implantation in 1949, himself noted these complications in his earliest patients.7 In his initial...

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Posterior capsule opacification in mice.

OBJECTIVE To present a new model of posterior capsule opacification (PCO) in mice. METHODS An extracapsular lens extraction was performed in 28 consecutive mice. Animals were humanely killed 0 and 24 hours and 3 and 14 days after surgery. Eyes were enucleated and processed for light microscopy and immunohistochemistry. RESULTS In 20 animals (71%), the eye appeared well healed before death. ...

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Risk factors for posterior capsule opacification.

I mprovements in techniques, instrumentation, and intraocular lens design appear to have been associated with declining rates of posterior capsule opacification following cataract surgery. While morbidity associated with posterior capsule opacification and its treatment, Nd:YAG laser capsulotomy, is limited, progressive opacification affects quality of vision and visual function, while capsulot...

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Systems of analysis of posterior capsule opacification.

This paper demonstrates the wide variety of systems for the analysis of posterior capsular opacification (PCO). No single system has been proved to be a gold standard and it is difficult to comment on the advantages of one system over another with the limited current knowledge on the effects of PCO on vision. There are few studies that actually compare the different systems of analysis. Researc...

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POCOman: new system for quantifying posterior capsule opacification.

PURPOSE To describe a new method of measuring posterior capsule opacification (PCO) and intraocular lens (IOL) rotation and report the validation of the method. SETTING Ophthalmology Department, St. Thomas' Hospital, and Medical Imaging, Department of Physics, King's College, London, United Kingdom. METHOD A new interactive software program, POCOman, was developed for the semiobjective asse...

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ژورنال

عنوان ژورنال: Experimental Eye Research

سال: 2016

ISSN: 0014-4835

DOI: 10.1016/j.exer.2015.04.021